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IGSF8 - Wikipedia, the free encyclopedia

IGSF8

From Wikipedia, the free encyclopedia


Immunoglobulin superfamily, member 8
Identifiers
Symbol(s) IGSF8; CD316; CD81P3; EWI2; PGRL
External IDs OMIM: 606644 MGI2154090 HomoloGene14163
Orthologs
Human Mouse
Entrez 93185 140559
Ensembl ENSG00000162729 ENSMUSG00000038034
Uniprot Q969P0 Q8R366
Refseq NM_052868 (mRNA)
NP_443100 (protein)
NM_080419 (mRNA)
NP_536344 (protein)
Location Chr 1: 158.33 - 158.34 Mb Chr 1: 174.1 - 174.16 Mb
Pubmed search [1] [2]

Immunoglobulin superfamily, member 8, also known as IGSF8, is a human gene.[1]IGSF8 has also been designated as CD316 (cluster of differentiation 316).



[edit] References

[edit] Further reading

  • Stipp CS, Kolesnikova TV, Hemler ME (2001). "EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily.". J. Biol. Chem. 276 (44): 40545-54. doi:10.1074/jbc.M107338200. PMID 11504738. 
  • Clark KL, Zeng Z, Langford AL, et al. (2001). "PGRL is a major CD81-associated protein on lymphocytes and distinguishes a new family of cell surface proteins.". J. Immunol. 167 (9): 5115-21. PMID 11673522. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Charrin S, Le Naour F, Labas V, et al. (2003). "EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells.". Biochem. J. 373 (Pt 2): 409-21. doi:10.1042/BJ20030343. PMID 12708969. 
  • Zhang XA, Lane WS, Charrin S, et al. (2003). "EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells.". Cancer Res. 63 (10): 2665-74. PMID 12750295. 
  • Bonkobara M, Das A, Takao J, et al. (2003). "Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.". Br. J. Dermatol. 148 (4): 654-64. PMID 12752121. 
  • Stipp CS, Kolesnikova TV, Hemler ME (2004). "EWI-2 regulates alpha3beta1 integrin-dependent cell functions on laminin-5.". J. Cell Biol. 163 (5): 1167-77. doi:10.1083/jcb.200309113. PMID 14662754. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Kolesnikova TV, Stipp CS, Rao RM, et al. (2004). "EWI-2 modulates lymphocyte integrin alpha4beta1 functions.". Blood 103 (8): 3013-9. doi:10.1182/blood-2003-07-2201. PMID 15070678. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Yang XH, Kovalenko OV, Kolesnikova TV, et al. (2006). "Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization.". J. Biol. Chem. 281 (18): 12976-85. doi:10.1074/jbc.M510617200. PMID 16537545. 
  • Sala-Valdés M, Ursa A, Charrin S, et al. (2006). "EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins.". J. Biol. Chem. 281 (28): 19665-75. doi:10.1074/jbc.M602116200. PMID 16690612. 
  • Kettner S, Kalthoff F, Graf P, et al. (2007). "EWI-2/CD316 is an inducible receptor of HSPA8 on human dendritic cells.". Mol. Cell. Biol. 27 (21): 7718-26. doi:10.1128/MCB.00180-07. PMID 17785435. 

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