CEACAM5
From Wikipedia, the free encyclopedia
|
Carcinoembryonic antigen-related cell adhesion molecule 5
|
|||||||||||
 |
|||||||||||
| PDB rendering based on 1e07. | |||||||||||
| Available structures: 1e07 | |||||||||||
| Identifiers | |||||||||||
| Symbol(s) | CEACAM5; CD66e; CEA; DKFZp781M2392 | ||||||||||
| External IDs | OMIM: 114890 | ||||||||||
|
|||||||||||
| Orthologs | |||||||||||
| Human | Mouse | ||||||||||
| Entrez | 1048 | n/a | |||||||||
| Ensembl | ENSG00000105388 | n/a | |||||||||
| Uniprot | P06731 | n/a | |||||||||
| Refseq | NM_004363 (mRNA) NP_004354 (protein) |
n/a (mRNA) n/a (protein) |
|||||||||
| Location | Chr 19: 46.9 - 46.92 Mb | n/a | |||||||||
| Pubmed search | [1] | n/a | |||||||||
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a human gene.[1]
Contents |
[edit] See also
[edit] References
[edit] Further reading
- Willcocks TC, Craig IW (1991). "Characterization of the genomic organization of human carcinoembryonic antigen (CEA): comparison with other family members and sequence analysis of 5' controlling region.". Genomics 8 (3): 492–500. PMID 2286372.
- Barnett T, Zimmermann W (1990). "Workshop report: proposed nomenclature for the carcinoembryonic antigen (CEA) gene family.". Tumour Biol. 11 (1-2): 59–63. PMID 2309067.
- Schrewe H, Thompson J, Bona M, et al. (1990). "Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression.". Mol. Cell. Biol. 10 (6): 2738–48. PMID 2342461.
- Kamarck ME, Elting JJ, Hart JT, et al. (1987). "Carcinoembryonic antigen family: expression in a mouse L-cell transfectant and characterization of a partial cDNA in bacteriophage lambda gt11.". Proc. Natl. Acad. Sci. U.S.A. 84 (15): 5350–4. PMID 2955415.
- Zimmermann W, Ortlieb B, Friedrich R, von Kleist S (1987). "Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure.". Proc. Natl. Acad. Sci. U.S.A. 84 (9): 2960–4. PMID 3033671.
- Barnett T, Goebel SJ, Nothdurft MA, Elting JJ (1989). "Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.". Genomics 3 (1): 59–66. PMID 3220478.
- Zimmermann W, Weber B, Ortlieb B, et al. (1988). "Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors.". Cancer Res. 48 (9): 2550–4. PMID 3356015.
- Beauchemin N, Benchimol S, Cournoyer D, et al. (1987). "Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen.". Mol. Cell. Biol. 7 (9): 3221–30. PMID 3670312.
- Oikawa S, Nakazato H, Kosaki G (1987). "Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.". Biochem. Biophys. Res. Commun. 142 (2): 511–8. PMID 3814146.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
- Hart SP, Ross JA, Ross K, et al. (2000). "Molecular characterization of the surface of apoptotic neutrophils: implications for functional downregulation and recognition by phagocytes.". Cell Death Differ. 7 (5): 493–503. doi:. PMID 10800083.
- Guignot J, Peiffer I, Bernet-Camard MF, et al. (2000). "Recruitment of CD55 and CD66e brush border-associated glycosylphosphatidylinositol-anchored proteins by members of the Afa/Dr diffusely adhering family of Escherichia coli that infect the human polarized intestinal Caco-2/TC7 cells.". Infect. Immun. 68 (6): 3554–63. PMID 10816511.
- Boehm MK, Perkins SJ (2000). "Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23.". FEBS Lett. 475 (1): 11–6. PMID 10854848.
- Screaton RA, DeMarte L, Dráber P, Stanners CP (2000). "The specificity for the differentiation blocking activity of carcinoembryonic antigen resides in its glycophosphatidyl-inositol anchor.". J. Cell Biol. 150 (3): 613–26. PMID 10931872.
- Bajenova OV, Zimmer R, Stolper E, et al. (2001). "Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells.". J. Biol. Chem. 276 (33): 31067–73. doi:. PMID 11406629.
- Wirth T, Soeth E, Czubayko F, Juhl H (2002). "Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth.". Clin. Exp. Metastasis 19 (2): 155–60. PMID 11964079.
- Louhimo J, Carpelan-Holmström M, Alfthan H, et al. (2002). "Serum HCG beta, CA 72-4 and CEA are independent prognostic factors in colorectal cancer.". Int. J. Cancer 101 (6): 545–8. doi:. PMID 12237895.
- Hampton R, Walker M, Marshall J, Juhl H (2002). "Differential expression of carcinoembryonic antigen (CEA) splice variants in whole blood of colon cancer patients and healthy volunteers: implication for the detection of circulating colon cancer cells.". Oncogene 21 (51): 7817–23. doi:. PMID 12420218.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
[edit] External links
 |
This membrane protein-related article is a stub. You can help Wikipedia by expanding it. |
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
