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CD109 - Wikipedia, the free encyclopedia

CD109

From Wikipedia, the free encyclopedia


CD109 molecule
Identifiers
Symbol(s) CD109; CPAMD7; DKFZp762L1111; FLJ38569; FLJ41966; RP11-525G3.1
External IDs OMIM: 608859 MGI2445221 HomoloGene25183
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 135228 235505
Ensembl ENSG00000156535 ENSMUSG00000046186
Uniprot Q6YHK3 Q8R422
Refseq NM_133493 (mRNA)
NP_598000 (protein)
XM_985933 (mRNA)
XP_991027 (protein)
Location Chr 6: 74.46 - 74.59 Mb Chr 9: 78.4 - 78.5 Mb
Pubmed search [1] [2]

CD109 (Cluster of Differentiation 109) is a human gene.[1]

CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system, implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990; Lin et al., 2002).[supplied by OMIM][1]

Contents

[edit] See also

[edit] References

[edit] Further reading

  • Lucas GF, Metcalfe P (2000). "Platelet and granulocyte glycoprotein polymorphisms.". Transfusion medicine (Oxford, England) 10 (3): 157–74. PMID 10972910. 
  • Sutherland DR, Yeo E, Ryan A, et al. (1991). "Identification of a cell-surface antigen associated with activated T lymphoblasts and activated platelets.". Blood 77 (1): 84–93. PMID 1984805. 
  • Kelton JG, Smith JW, Horsewood P, et al. (1990). "Gova/b alloantigen system on human platelets.". Blood 75 (11): 2172–6. PMID 2346781. 
  • Lin M, Sutherland DR, Horsfall W, et al. (2002). "Cell surface antigen CD109 is a novel member of the alpha(2) macroglobulin/C3, C4, C5 family of thioester-containing proteins.". Blood 99 (5): 1683–91. PMID 11861284. 
  • Schuh AC, Watkins NA, Nguyen Q, et al. (2002). "A tyrosine703serine polymorphism of CD109 defines the Gov platelet alloantigens.". Blood 99 (5): 1692–8. PMID 11861285. 
  • Giesert C, Marxer A, Sutherland DR, et al. (2003). "Antibody W7C5 defines a CD109 epitope expressed on CD34+ and CD34- hematopoietic and mesenchymal stem cell subsets.". Ann. N. Y. Acad. Sci. 996: 227–30. PMID 12799300. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Solomon KR, Sharma P, Chan M, et al. (2004). "CD109 represents a novel branch of the alpha2-macroglobulin/complement gene family.". Gene 327 (2): 171–83. doi:10.1016/j.gene.2003.11.025. PMID 14980714. 
  • Zhang JM, Hashimoto M, Kawai K, et al. (2005). "CD109 expression in squamous cell carcinoma of the uterine cervix.". Pathol. Int. 55 (4): 165–9. doi:10.1111/j.1440-1827.2005.01807.x. PMID 15826242. 
  • Lewandrowski U, Moebius J, Walter U, Sickmann A (2006). "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.". Mol. Cell Proteomics 5 (2): 226–33. doi:10.1074/mcp.M500324-MCP200. PMID 16263699. 
  • Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952. 
  • Finnson KW, Tam BY, Liu K, et al. (2006). "Identification of CD109 as part of the TGF-beta receptor system in human keratinocytes.". FASEB J. 20 (9): 1525–7. doi:10.1096/fj.05-5229fje. PMID 16754747. 
  • Sjöblom T, Jones S, Wood LD, et al. (2006). "The consensus coding sequences of human breast and colorectal cancers.". Science 314 (5797): 268–74. doi:10.1126/science.1133427. PMID 16959974. 
  • Hasegawa M, Hagiwara S, Sato T, et al. (2007). "CD109, a new marker for myoepithelial cells of mammary, salivary, and lacrimal glands and prostate basal cells.". Pathol. Int. 57 (5): 245–50. doi:10.1111/j.1440-1827.2007.02097.x. PMID 17493171. 

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