Serotonin uptake inhibitor

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A serotonin uptake inhibitor is a drug which acts as a neurotransmitter uptake inhibitor on serotonin receptors.

1 Types
2 Examples
3 References
4 External links

[edit] Types

The most well known members of this class are the selective serotonin reuptake inhibitors (SSRI)s.

However, there also exist non-selective inhibitors. In some cases, such as the older antidepressants clomipramine and trazodone, this lack of selectivity is seen as a disadvantage, and is one of the reasons those drugs are currently prescribed less frequently.

In other cases, such as duloxetine and milnacipran, the lack of selectivity is considered part of the normal profile of the medication, and it is classified accordingly.

[edit] Examples

Examples of serotonin uptake inhibitors include:^[1]

[edit] References

^ MeSH list of agents 82017367

[edit] External links

MeSH Serotonin+uptake+inhibitors

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v • d • e Receptor agonists, antagonists, and reuptake inhibitors

BA/M: 5-HT (serotonin) receptor	Serotonin receptor agonist • Serotonin antagonist (5-HT₃) • Serotonin uptake inhibitor (SSRI)

BA/M: Dopamine receptor	Dopamine agonist • Dopamine antagonist • Dopamine reuptake inhibitor

BA/M: Adrenergic receptor	Adrenergic agonist (Alpha, Beta₂) • Adrenergic antagonist (Alpha, Beta) • Adrenergic uptake inhibitor

BA/M: Histamine receptor	Histamine agonist • Histamine antagonist (H₁, H₂)

Acetylcholine receptor	Cholinergic (Muscarinic, Nicotinic) • Anticholinergic (Muscarinic, Nicotinic) • Acetylcholinesterase inhibitor

AA: GABA receptor	GABA agonist • GABA antagonist

AA: Glutamate receptor	NMDA receptor (NMDA receptor antagonist)

v • d • e

Psychoanaleptics: antidepressants (N06A)

MAOIs

Iproclozide • Iproniazid • Isocarboxazid • Minaprine • Nialamide • Pargyline • Phenelzine • Rasagiline • Selegiline • Toloxatone • Tranylcypromine
RIMAs: Befloxatone • Brofaromine • Cimoxatone • Beta-carbolines (Harmaline) • Moclobemide

RIs

S RI	SS RI (Alaproclate, Citalopram, Dapoxetine, Escitalopram, Femoxetine, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Zimelidine) • TCAs/Tetras (Clomipramine, Nefazodone, Trazodone)

N RI / A RI	Atomoxetine • Maprotiline • Nisoxetine • Reboxetine • Talopram • Viloxazine • TCAs/Tetras (Amitriptyline, Amoxapine, Butriptyline, Desipramine/Lofepramine, Dibenzepin, Dosulepin, Doxepin, Imipramine, Iprindole, Melitracen, Nortriptyline, Protriptyline, Trimipramine, Maprotiline)

D RI	Medifoxamine • Phenmetrazine • Vanoxerine • TCAs (Amineptine)

SN RI	Bicifadine • Desvenlafaxine • Duloxetine • Milnacipran • Nefazodone • Venlafaxine

ND RI	Bupropion • Nomifensine

SND RI	Brasofensine • Diclofensine • Tesofensine