Nisoxetine
From Wikipedia, the free encyclopedia
Nisoxetine
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Systematic (IUPAC) name | |
3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine | |
Identifiers | |
CAS number | |
ATC code | ? |
PubChem | |
Chemical data | |
Formula | C17H21NO2 |
Mol. mass | 271.354 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
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Legal status | |
Routes | ? |
Nisoxetine (LY-94939) is a drug which inhibits the reuptake of norepinephrine (noradrenaline). It is a racemic compound with two isomers.
[edit] Uses
Nisoxetine is not currently used in humans,[1] but was originally researched as an antidepressant and is now widely used in scientific research as a standard selective noradrenaline reuptake inhibitor.[2]
[edit] References
- ^ Kelwala S, Stanley M, Gershon S. History of antidepressants: successes and failures. Journal of Clinical Psychiatry. 1983 May;44(5 Pt 2):40-8.PMID 6222036
- ^ Graham D, Langer SZ. Advances in sodium-ion coupled biogenic amine transporters. Life Sciences. 1992;51(9):631-45.PMID 1501510
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