From Wikipedia, the free encyclopedia
Bone morphogenetic protein 8A (BMP8A) is a polypeptide member of the TGFβ superfamily of proteins. It, like other bone morphogenetic proteins (BMPs) is involved in the development of bone and cartilage. BMP8A may be involved in epithelial osteogenesis. It also plays a role in bone homeostasis. It is a disulfide-linked homodimer.
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Cell signaling: TGF beta signaling pathway |
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| TGF beta superfamily of ligands |
TGF beta family ( TGF-β1, TGF-β2, TGF-β3)
Bone morphogenetic proteins ( BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, BMP8a, BMP8b, BMP10 , BMP15)
Growth differentiation factors ( GDF1, GDF2, GDF3, GDF5, GDF6, GDF7, Myostatin/GDF8, GDF9, GDF10, GDF11, GDF15)
Other ( Activin A and B/ Inhibin A and B, Anti-müllerian hormone, Nodal)
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| TGF beta receptors |
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| Transducers/SMAD |
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| Ligand Inhibitors |
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| Coreceptors |
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| Other |
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