Mebhydrolin

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Mebhydrolin
Systematic (IUPAC) name
9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-β-carboline
Identifiers
CAS number	524-81-2 6153-33-9[1]
ATC code	R06AX15
PubChem	10458737
Chemical data
Formula	C19H20N2[2]
Mol. mass	276.376 g/mol
SMILES	eMolecules & PubChem
Synonyms	Incidal, Omeril, diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[3]
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	Not established[4]
Legal status
Routes	oral[4]

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries. It is also called Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.^[5]

[edit] References

1. ^ Diazoline (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved on 2007-03-02.
2. ^ Mebhydrolin chemical information (HTML). PubChem. Retrieved on 2007-03-02.
3. ^ Mebhydroline (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved on 2007-03-02.
4. ^ ^{a b} FABAHISTIN 50 mg (Tablets) (HTML). South African Electronic Package Inserts (1970-09). Retrieved on 2007-03-02.
5. ^ Franks, HM; M. Lawrie, VV Schabinsky, GA Starmer, RK Teo (1981-10-31). Interaction between ethanol and antihistamines: 3. mebhydrolin. (HTML) (English). Med J Aust.. Retrieved on 2007-03-02.

v • d • e Antihistamines (primarily R06) Aminoalkyl ethers Bromazine/Bromodiphenhydramine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine Substituted alkylamines Brompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine Substituted ethylenediamines Chloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine) Phenothiazine derivatives Alimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine Piperazine derivatives Buclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide Others for systemic use Antazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine) For topical use Bamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine Antiallergic agents excluding corticosteroids Antazoline • Azelastine Other antiallergics Emedastine • Epinastine • Ketotifen • Montelukast • Olopatadine