SLC20A2

From Wikipedia, the free encyclopedia

Solute carrier family 20 (phosphate transporter), member 2

Identifiers

SLC20A2; GLVR2; Glvr-2; MLVAR; PIT-2

External IDs

OMIM: 158378 MGI: 97851 HomoloGene: 68531

Gene ontology
Molecular Function:	• receptor activity • inorganic phosphate transmembrane transporter activity • sodium:phosphate symporter activity
Cellular Component:	• membrane fraction • integral to plasma membrane • membrane
Biological Process:	• transport • phosphate transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006749 (mRNA)
NP_006740 (protein)

NM_011394 (mRNA)
NP_035524 (protein)

Location

Chr 8: 42.39 - 42.52 Mb

Chr 8: 23.94 - 24.04 Mb

Pubmed search

[1]

[2]

Solute carrier family 20 (phosphate transporter), member 2, also known as SLC20A2, is a human gene.^[1]

[edit] See also

Solute carrier family

[edit] References

^ Entrez Gene: SLC20A2 solute carrier family 20 (phosphate transporter), member 2.

[edit] Further reading

Garcia JV, Jones C, Miller AD (1991). "Localization of the amphotropic murine leukemia virus receptor gene to the pericentromeric region of human chromosome 8.". J. Virol. 65 (11): 6316-9. PMID 1656098.
Kozak SL, Siess DC, Kavanaugh MP, et al. (1995). "The envelope glycoprotein of an amphotropic murine retrovirus binds specifically to the cellular receptor/phosphate transporter of susceptible species.". J. Virol. 69 (6): 3433-40. PMID 7745689.
van Zeijl M, Johann SV, Closs E, et al. (1994). "A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family.". Proc. Natl. Acad. Sci. U.S.A. 91 (3): 1168-72. PMID 8302848.
Salaün C, Gyan E, Rodrigues P, Heard JM (2002). "Pit2 assemblies at the cell surface are modulated by extracellular inorganic phosphate concentration.". J. Virol. 76 (9): 4304-11. PMID 11932396.
Bottger P, Pedersen L (2003). "Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function.". J. Biol. Chem. 277 (45): 42741-7. doi:10.1074/jbc.M207096200. PMID 12205090.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Bøttger P, Pedersen L (2004). "The central half of Pit2 is not required for its function as a retroviral receptor.". J. Virol. 78 (17): 9564-7. doi:10.1128/JVI.78.17.9564-9567.2004. PMID 15308749.
Bøttger P, Pedersen L (2005). "Evolutionary and experimental analyses of inorganic phosphate transporter PiT family reveals two related signature sequences harboring highly conserved aspartic acids critical for sodium-dependent phosphate transport function of human PiT2.". FEBS J. 272 (12): 3060-74. doi:10.1111/j.1742-4658.2005.04720.x. PMID 15955065.
Bøttger P, Hede SE, Grunnet M, et al. (2007). "Characterization of transport mechanisms and determinants critical for Na+-dependent Pi symport of the PiT family paralogs human PiT1 and PiT2.". Am. J. Physiol., Cell Physiol. 291 (6): C1377-87. doi:10.1152/ajpcell.00015.2006. PMID 16790504.
Ravera S, Virkki LV, Murer H, Forster IC (2007). "Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements.". Am. J. Physiol., Cell Physiol. 293 (2): C606-20. doi:10.1152/ajpcell.00064.2007. PMID 17494632.

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v • d • e Membrane proteins, carrier proteins: membrane transport proteins

ABC-transporter	A1, A2, A3, A4, A7, A8, A12, B1 B2-3, B2, B3, B4, B5, B6, B7, B9, B11 C1, C2, C3, C4, C5, C6, C8, C8-9, C10, C13, C11 D1, D2, D3, D4, E1, F1, F2 G1, G2, G4, Sterolin (G5, G8)

Solute carrier	1A1-7, 1A1, 1A2, 1A3, 1A4, 1A5, 2A1, 2A2, 2A3, 2A4, 2A5, 2A6, 2A8, 2A9, 2A10, 2A12, 3A1, 3A2, 4A1, 4A2, 4A3, 4A4, 4A5, 4A7, 4A8, 4A11, 5A1-2, 5A1, 5A3, 5A5, 5A8, 6A1, 6A2, 6A3, 6A4, 6A5, 6A8, 6A9, 6A19, 7A1, 7A2, 7A3, 7A4, 7A5, 7A7, 7A8, 7A9, 7A11, 8A1-3, 9A1, 9A2, 9A3, 9A3R1, 9A3R2, 9A5, 9A6, 9A8, 10A1, 10A2, 10A3, 10A7, 11A1, 11A2, 11A3, 12A1-2, 12A3, 12A4, 12A5, 12A6, 12A7, 14A1, 13A3, 14A2, 15A1, 15A2, 16A1, 16A2, 16A3, 16A4, 17A1, 17A5, 17A6-8, 17A7, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 20A1, 20A2, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 22A7, 22A9, 22A11, 22A12, 22A18, 23A1, 23A2, 24A1-2, 24A5, 25A1, 25A3, 25A4, 25A4-6, 25A8, 25A10, 25A11, 25A12, 25A13, 25A14, 25A15, 25A17, 25A19, 25A20, 25A27, 25A31, 25A37, 25A39, 26A2, 26A3, 26A4, 26A5, 26A6, 26A7, 26A8, 27A1, 27A2, 27A3, 27A4, 28A1, 28A2, 29A1, 29A2, 29A4, 30A4, 30A7, 30A8, 31A1, 31A2, 32A1, 34A1, 34A2, 34A3, 35A1, 35A2, 35B2, 35B4, 35C1, 36A1, 37A4, 38A2, 38A3, 39A1, 39A2, 39A3, 39A4, 39A6, 39A7, 40A1, 43A1 44A1, 44A2, 44A4, 45A2, O1A2, O1B1, O1B3, O2B1, O431, O4A1

Monosaccharide	GLUT1, GLUT2, GLUT3, GLUT4, GLUT5, GLUT6, GLUT8, GLUT9

Other	Amino acid (CD98) - Fatty acid (CD36) - Ion channels - Ion pumps - Mitochondrial membrane transport protein - Neurotransmitter transport proteins - Nuclear (Importin, Karyopherin)