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Gestational trophoblastic disease - Wikipedia, the free encyclopedia

Gestational trophoblastic disease

From Wikipedia, the free encyclopedia

Gestational trophoblastic disease
Classification and external resources
DiseasesDB 2602
MedlinePlus 001496
eMedicine med/866 
MeSH D031901

Gestational trophoblastic disease is any type of abnormal proliferation of trophoblasts during pregnancy. Types include:

  • abnormal placenta, mostly due to abnormal fertilization
  • frank malignant tumors of trophoblast
    • invasive mole, choriocarcinoma (CCA)
    • placental site trophoblastic tumor (PSTT)
    • epithelioid trophoblastic tumor (ETT)
  • not true neoplasms, representing abnormally formed placentas
    • exaggerated placenta site (EPS)
    • placental site nodule (PSN)

Contents

[edit] Treatment

Methotrexate and dactinomycin are among the chemotherapy drugs proposed for this condition.[1]

Molar pregnancies may be considered benign melanoma.

[edit] See also

[edit] References

  1. ^ Abrão RA, de Andrade JM, Tiezzi DG, Marana HR, Dos Reis FJ, Clagnan WS (2007). "Treatment for low-risk gestational trophoblastic disease: Comparison of single-agent methotrexate, dactinomycin and combination regimens". Gynecologic Oncology 108: 149. doi:10.1016/j.ygyno.2007.09.006. PMID 17931696. 

[edit] External links

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