Dapagliflozin
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Dapagliflozin | |
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IUPAC name | (2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol |
Other names | BMS-512148
(1S)-1,5-anhydro-1-C-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-D-glucitol |
Identifiers | |
CAS number | [461432-26-8] |
SMILES | [H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c2cc(Cc3ccc(OCC)cc3)c(Cl)cc2 |
InChI | 1/C21H25ClO6/c1-2-27- 15-6-3-12(4-7-15)9- 14-10-13(5-8-16(14)22)21- 20(26)19(25)18(24)17(11- 23)28-21/h3-8,10,17-21, 23-26H,2,9,11H2,1H3/t17-, 18-,19+,20-,21+/m1/s1 |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Dapagliflozin (rINN/USAN) is an experimental SGLT2 inhibitor being studied by Bristol-Myers Squibb as a potential treatment for type 1 and 2 diabetes.[1]
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