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OR8G1 - Wikipedia, the free encyclopedia

OR8G1

From Wikipedia, the free encyclopedia


Olfactory receptor, family 8, subfamily G, member 1
Identifiers
Symbol(s) OR8G1; HSTPCR25; OR8G1P; TPCR25
External IDs MGI3030801 HomoloGene81579
Orthologs
Human Mouse
Entrez 26494 258086
Ensembl ENSG00000197849 ENSMUSG00000055820
Uniprot Q15617 n/a
Refseq NM_001002905 (mRNA)
NP_001002905 (protein)
NM_001011826 (mRNA)
NP_001011826 (protein)
Location Chr 11: 123.63 - 123.64 Mb Chr 9: 39.5 - 39.5 Mb
Pubmed search [1] [2]

Olfactory receptor, family 8, subfamily G, member 1, also known as OR8G1, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

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[edit] Further reading

  • Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.". Genomics 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360. 
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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