OR6A2
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 6, subfamily A, member 2
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| Identifiers | ||||||||||||||
| Symbol(s) | OR6A2; I7; MGC126538; MGC126540; OR11-55; OR6A1; OR6A2P | |||||||||||||
| External IDs | OMIM: 608495 MGI: 97432 HomoloGene: 2743 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 8590 | 18317 | ||||||||||||
| Ensembl | ENSG00000184933 | ENSMUSG00000070417 | ||||||||||||
| Uniprot | O95222 | n/a | ||||||||||||
| Refseq | NM_003696 (mRNA) NP_003687 (protein) |
NM_010983 (mRNA) NP_035113 (protein) |
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| Location | Chr 11: 6.77 - 6.77 Mb | Chr 7: 106.79 - 106.8 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 6, subfamily A, member 2, also known as OR6A2, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Buettner JA, Glusman G, Ben-Arie N, et al. (1998). "Organization and evolution of olfactory receptor genes on human chromosome 11.". Genomics 53 (1): 56–68. doi:. PMID 9787077.
- Lane RP, Cutforth T, Young J, et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci.". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:. PMID 11416212.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:. PMID 15489334.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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