Gallamine
From Wikipedia, the free encyclopedia
 |
This article does not cite any references or sources. (January 2008) Please help improve this article by adding citations to reliable sources. Unverifiable material may be challenged and removed. |
 |
|
|
Gallamine
|
|
| Systematic (IUPAC) name | |
| N-[2-[2,3-bis (2-diethylaminoethoxy) phenoxy]ethyl]- N-ethyl-ethanamine | |
| Identifiers | |
| CAS number | |
| ATC code | M03 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C24H45N3O3 C30H60N3O3+3 · 3 I- (gallamine triethiodide) |
| Mol. mass | 423.633 g/mol 891.529 g/mol (triethiodide) |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Gallamine (as gallamine triethiodide) is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release.
Gallamine is commonly used to stabilize muscle contractions during surgical procedures.
|
|||||||||||||||||||||||||||||||||
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
