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UPSK RNA |
|
Type: |
Cis-reg; |
2° structure: |
Published; PubMed |
Seed alignment: |
PubMed |
Avg length: |
23.0 nucleotides |
Avg identity: |
97% |
|
The Upstream pseudoknot (UPSK) is an RNA element found in turnip yellow mosaic virus which is thought to be needed for efficient transcription. Disruption of the pseudoknot structure gives rise to a 50% drop in transcription efficiency.[1] This element acts in conjunction with the Tymovirus/Pomovirus tRNA-like 3' UTR element to enhance translation.[2]
[edit] References
- ^ Deiman, BA; Kortlever RM, Pleij CW (1997). "The role of the pseudoknot at the 3' end of turnip yellow mosaic virus RNA in minus-strand synthesis by the viral RNA-dependent RNA polymerase". J Virol 71: 5990–5996. PMID 9223489.
- ^ Matsuda, D; Dreher TW (2004). "The tRNA-like structure of Turnip yellow mosaic virus RNA is a 3'-translational enhancer". Virology 321: 36–46. doi:10.1016/j.virol.2003.10.023. PMID 15033563.
[edit] External links