Sterol 3beta-glucosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a sterol 3beta-glucosyltransferase (EC 2.4.1.173) is an enzyme that catalyzes the chemical reaction

UDP-glucose + a sterol $\rightleftharpoons$ UDP + a sterol 3-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and sterol, whereas its two products are UDP and sterol 3-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:sterol 3-O-beta-D-glucosyltransferase. Other names in common use include UDPG:sterol glucosyltransferase, UDP-glucose-sterol beta-glucosyltransferase, sterol:UDPG glucosyltransferase, UDPG-SGTase, uridine diphosphoglucose-poriferasterol glucosyltransferase, uridine diphosphoglucose-sterol glucosyltransferase, sterol glucosyltransferase, sterol-beta-D-glucosyltransferase, and UDP-glucose-sterol glucosyltransferase.

[edit] References

IUBMB entry for 2.4.1.173
BRENDA references for 2.4.1.173 (Recommended.)
PubMed references for 2.4.1.173
PubMed Central references for 2.4.1.173
Google Scholar references for 2.4.1.173
Duperon R and Duperon P (1987). "Intracellular-localization of UDP-glucose-sterol glucosyl transferase and UDP-galactose-sterol galactosyl transferase activities in the leaves of tomato (Solanum lycopersicon L, Solanaceae)". C.R. Acad. Sci. Paris, Ser. 3 304: 235–238.
Kalinowska M and Wojciechowski ZA (1986). "Enzymatic-synthesis of nuatigenin 3-beta-D-glucoside in oat (Avena sativa) leaves". Phytochemistry 25: 2525–2529.
Kalinowska M and Wojciechowski ZA (1987). "Subcellular-localization of UDPG-nuatigenin glucosyltransferase in oat leaves". Phytochemistry 26: 353–357.
Murakami-Murofushi K, Ohta J (1989). "Expression of UDP-glucose: poriferasterol glucosyltransferase in the process of differentiation of a true slime mold, Physarum polycephalum". Biochim. Biophys. Acta. 992: 412–5. PMID 2528379.
Wojciechowski ZA, Zimowski J and Tyski S (1977). "Enzymatic synthesis of steryl 3beta-D-monoglucosides in the slime mold Physarum polycephalum". Phytochemistry 16: 911–914.