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SraJ RNA - Wikipedia, the free encyclopedia

SraJ RNA

From Wikipedia, the free encyclopedia

SraJ RNA
Template:Abbreviation
Type: Gene; sRNA;
2° structure: Predicted; PFOLD
Seed alignment: Bateman A
Avg length: 173.9 nucleotides
Avg identity: 91%

SraJ is a is a small non-coding RNA (ncRNA). It is the functional product of a gene which is not translated into protein.

This ncRNA was discovered in the bacteria Escherichia coli during a large scale computational screen for transcription signals and genomic features of known small RNA-encoding genes[1]. During this screen 14 novel ncRNA genes were identified.

The expression of SraJ was experimentally confirmed by Northern blotting[1]. This ncRNA is expressed in early logarithmic phase, but its level decreases into stationary phase. Northern blot analysis also indicated this RNA undergoes specific cleavage processing. The function of this RNA is unknown.

[edit] References

  1. ^ a b Argaman L, Hershberg R, Vogel J, et al (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli". Curr. Biol. 11 (12): 941–50. PMID 11448770. 

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