Sommelet reaction
From Wikipedia, the free encyclopedia
The Sommelet reaction is an organic reaction in which a benzyl halide is converted to an aldehyde by action of hexamine and water [1][2][3].
A conceptually related reaction is the Duff reaction (halide replaced by an arene).
In the Kröhnke aldehyde synthesis [4] the oxidizing reagent is is a combination of pyridine and p-nitrosodimethylaniline.
[edit] References
- ^ Marcel Sommelet (1913). "Sur un mode de décomposition des halogénoalcoylates d'hexaméthylène - tétramine". Compt. rend. 157: 852–854.
- ^ March, Jerry (1985). Advanced Organic Chemistry, Reactions, Mechanisms and Structure, third Edition, John Wiley & Sons. ISBN 0-471-85472-7.
- ^ For an example see: Organic Syntheses, Coll. Vol. 4, p.918 (1963); Vol. 33, p.93 (1953). http://www.orgsynth.org/orgsyn/pdfs/CV4P0918.pdf
- ^ F. Kröhnke, Ber., 71B, 2583 (1938).
