Salsalate
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Salsalate
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| Systematic (IUPAC) name | |
| 2-(2-Hydroxybenzoyl)oxybenzoic acid | |
| Identifiers | |
| CAS number | |
| ATC code | N02 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C14H10O5 |
| Mol. mass | 258.23 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Salsalate is a non-steroidal anti-inflammatory drug (NSAID). Salsalate is in a class of drugs called salicylates. Salsalate may work by inhibiting the production of and release of prostaglandins. Salsalate is the generic name of a prescription drug marketed under the brandnames Mono-Gesic, Salflex, Disalcid, and Salsitab. Other generic and brand name formulations may be available.[1]
[edit] Typical Use
Salsalate is used to reduce pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis, and related rheumatic conditions.
"In contrast to aspirin, salsalate causes no greater fecal gastrointestinal blood loss than placebo." [2]
[edit] Research on use to prevent or treat Type II Diabetes
The Wall Street Journal Health Blog reported on research on using Salsalate to prevent or treat type II diabetes: "In a 20-patient, month-long study, the fasting glucose levels of those who took salsalate declined 13% compared with those who took a placebo. The results, published in the Feb. issue of Diabetes Care, suggest that the drug reduces blood sugar in obese adults who don’t have diabetes, apparently by making insulin work better."[3]
[edit] References
- ^ drugs.com Salsalate entry [1]
- ^ DrugBank: DB01399 (Salsalate)
- ^ Aspirin cousin could help prevent diabetes blogs.wsj.com
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