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Rutin - Wikipedia, the free encyclopedia

Rutin

From Wikipedia, the free encyclopedia

Rutin
Rutin
IUPAC name 2-(3,4-dihydroxyphenyl)-
4,5-dihydroxy-3-[3,4,5-
trihydroxy-6-[(3,4,5-
trihydroxy-6-methyl-
oxan-2-yl)oxymethyl]
oxan-2-yl]oxy-chromen-
7-one
Identifiers
CAS number [153-18-4]
SMILES xxxxx
Properties
Molecular formula C27H30O16
Molar mass 610.52 g/mol
Density x.xxx g/cm3
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Rutin, also called rutoside, quercetin-3-rutinoside and sophorin, is a citrus flavonoid glycoside found in buckwheat[1] , the leaves and petioles of Rheum species, and the fruit of the Fava D'Anta tree (from Brazil), as well as other sources. Its name comes from the name of Ruta graveolens, a plant, that also contains rutin. Rutin is the glycoside between the flavonol quercetin and the disaccharide rutinose.

It can combine with cations, supplying nutrients from the soil to the cells in plants. In humans, it attaches to the iron ion Fe2+, preventing it from binding to hydrogen peroxide, which would otherwise create a highly-reactive free-radical that may damage cells. It is also an antioxidant, and therefore plays a role in inhibiting some cancers.

Rutin also strengthens the capillaries, and, therefore, can reduce the symptoms of haemophilia. It also may help to prevent a common unpleasant-looking venous edema of the legs. Rutin, as ferulic acid, can reduce the cytotoxicity of oxidized LDL cholesterol and lower the risk of heart disease.

Rutin has a veterinary use in the management of chylothorax in dogs.

[edit] References

  1. ^ Kreft S, Knapp M, Kreft I (November 1999). "Extraction of rutin from buckwheat (Fagopyrum esculentum Moench) seeds and determination by capillary electrophoresis". Journal of Agricultural and Food Chemistry 47 (11): 4649–4652. doi:10.1021/jf990186p. 


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