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Polyglycylation is a form of posttranslational modification of glutamate residues of the carboxyl-terminal region tubulin in certain microtubules (eg axonemal) originally discovered in paramecium[1], and later shown in mammalian neurons as well[2].
[edit] References
- ^ Redeker, V., Levilliers, N., Schmitter, J.M., Le Caer, J.P., Rossier, J., Adoutte, A., and Bré, M.H. (1994). "Polyglycylation of tubulin: a posttranslational modification in axonemal microtubules". Science 266 (5191): 1688–91. doi:10.1126/science.7992051. PMID 7992051.
- ^ Banerjee Asok (2002). "Coordination of posttranslational modifications of bovine brain alpha-tubulin. Polyglycylation of delta2 tubulin". J. Biol. Chem. 277 (48): 46140–4. doi:10.1074/jbc.M208065200. PMID 12356754.