PDLIM4

From Wikipedia, the free encyclopedia

PDZ and LIM domain 4

Identifiers

External IDs

OMIM: 603422 MGI: 1353470 HomoloGene: 2735

Gene ontology
Molecular Function:	• protein binding • zinc ion binding • metal ion binding

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003687 (mRNA)
NP_003678 (protein)

NM_019417 (mRNA)
NP_062290 (protein)

Location

Chr 5: 131.62 - 131.64 Mb

Chr 11: 53.9 - 53.91 Mb

Pubmed search

[1]

[2]

PDZ and LIM domain 4, also known as PDLIM4, is a human gene.^[1]

[edit] References

^ Entrez Gene: PDLIM4 PDZ and LIM domain 4.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Bashirova AA, Markelov ML, Shlykova TV, et al. (1998). "The human RIL gene: mapping to human chromosome 5q31.1, genomic organization and alternative transcripts.". Gene 210 (2): 239-45. PMID 9573374.
Cuppen E, van Ham M, Wansink DG, et al. (2000). "The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL.". Eur. J. Cell Biol. 79 (4): 283-93. PMID 10826496.
Walma T, Spronk CA, Tessari M, et al. (2002). "Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL.". J. Mol. Biol. 316 (5): 1101-10. doi:10.1006/jmbi.2002.5402. PMID 11884147.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Omasu F, Ezura Y, Kajita M, et al. (2003). "Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women.". J. Hum. Genet. 48 (7): 342-5. doi:10.1007/s10038-003-0035-1. PMID 12908099.
Vallenius T, Scharm B, Vesikansa A, et al. (2004). "The PDZ-LIM protein RIL modulates actin stress fiber turnover and enhances the association of alpha-actinin with F-actin.". Exp. Cell Res. 293 (1): 117-28. PMID 14729062.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315-23. doi:10.1101/gr.2122004. PMID 15231747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
van den Berk LC, van Ham MA, te Lindert MM, et al. (2005). "The interaction of PTP-BL PDZ domains with RIL: an enigmatic role for the RIL LIM domain.". Mol. Biol. Rep. 31 (4): 203-15. PMID 15663004.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Schwartz LM, Woloshin S, Birkmeyer JD (2005). "How do elderly patients decide where to go for major surgery? Telephone interview survey.". BMJ 331 (7520): 821. doi:10.1136/bmj.38614.449016.DE. PMID 16192286.
Boumber YA, Kondo Y, Chen X, et al. (2007). "RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.". Cancer Res. 67 (5): 1997-2005. doi:10.1158/0008-5472.CAN-06-3093. PMID 17332327.