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Oxacillin - Wikipedia, the free encyclopedia

Oxacillin

From Wikipedia, the free encyclopedia

Oxacillin
Systematic (IUPAC) name
(2R,5R,6S)-3,3-dimethyl-6-[(5-methyl-3-phenyl-
1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-
azabicyclo[3.2.0]heptane-2-carboxylic acid
Identifiers
CAS number 66-79-5
ATC code J01CF01 J01CF04
PubChem 6196
Chemical data
Formula C19H19N3O5S 
Mol. mass 401.437 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Oxacillin sodium (trade name Bactocill) is a narrow spectrum beta-lactam antibiotic of the penicillin class. It is resistant to penicillinases, such as that produced by Staphylococcus aureus. However, resistant strains are now emerging that are called oxacillin-resistant Staphylococcus aureus (ORSA). It is widely used clinically in the US, but in the UK is only used for laboratory identification of resistant organisms. including MRSA and Streptococcus pneumoniae).


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