Nested case-control study
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A nested case-control study is a type of study design where new case controls are applied into cohorts that were defined before the study begins.
Compared with case-control study, nested case-control study can reduce 'recall bias' and temporal ambiguity, and compared with cohort study, it can reduce cost and save time.
The drawback of nested case-control study is non-diseased persons from whom the controls are selected may not be fully representative of the original cohort, due to death or failure to follow-up cases.
[edit] Similar termss
A case-control study in which cases and controls are drawn from within a prospective study. All cases who developed the outcome of interest during the follow-up are selected and compared with a subgroup of the non-cases. Exposure is defined prior to disease development based on data collected at baseline or on assays conducted in biological samples collected at baseline.
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This type of study can be developed from a Descriptive study for example in a study on Prevalance of dental caries the children were further divided into groups with daily brushing,Infrequent and NoBrushing.This can be used to make valid comparison to test the hypothesis in relation to Bushing as a habit to reduce the prevalnce of Dental Caries.
