Talk:Natural killer cell
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Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) While Natural Killer cells are a subset of lymphocytes, they are not included in the cytotoxic T lymphocyte class. They have a different surface profile although sharing most due to common ancestry. |
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[edit] Natural Killer cell → Natural killer cell
As an Natural Killer cell researcher, I believe that "Natural killer cell" should be the prefered wikipedia entry name. "Natural Killer Cell" is the universal nomenclature when describing natural killer cells. "Natural killer lymphocyte", while a techincally correct term, is rarely, if ever used by researchers and should be merged with "Natural killer cell".—Preceding unsigned comment added by Clermeil (talk • contribs) 07:00, 27 June 2006
I agree that "Natural Killer (NK) cell" should be the Wikipedia entry name. Indeed, the term lymphocyte is best restricted to those cells that rearrange their antigen receptor (immunoglobulin or T-cell receptor [TCR]) genes. Thus 'Natural Killer lymphocyte' would be incorrect for classical NK cells under this definition. There is a population of cells with NK cell characteristics that do rearrange their TCR genes and these are referred to as NKT cells.—Preceding unsigned comment added by Regfpjd (talk • contribs) 01:37, 30 June 2006
[edit] Natural killer T cell
A clear distinction needs to be made between "Natural killer cell" and "Natural killer T cell", with their own wikipedia entries. They also need to be mentioned separately within the lymphocyte and white blood cell articles.—Preceding unsigned comment added by 129.132.232.242 (talk • contribs) 02:55, 9 July 2006
- They do have their own pages now.--DO11.10 01:58, 8 November 2006 (UTC)
is it not a bit misleading that typing in Killer T cell gets redirected to NK Cell page - i thought that they were actually 2 different cells; the former requiring MHC1 to recognise the antigen and the latter not requiring it? 04:45, 7 November 2006 —Preceding unsigned comment added by Maryhanc (talk • contribs) Please sign your posts.
- Yup you are right, it has been fixed--DO11.10 01:58, 8 November 2006 (UTC)
[edit] Some Changes
I added the section on discovery, and I hope to do some significant restructing and organizing of this article. Let me know what you think! Cacofonie 04:00, 21 December 2006 (UTC)
- Fantastic start! Good luck with the article, it is in serious need of some attention. Now that you've jumped in and started making it look pretty, I'm sure others will follow. I might even pop in at some stage, haha. Thanks for your interest -- Serephine ♠ talk - 04:12, 21 December 2006 (UTC)
Added a section on activation. I realize its a little redundant with the stuff further on, but, I hope add a section dedicated to NK-cell receptors, as well as a section on 'Missing Self'Cacofonie 19:20, 24 December 2006 (UTC)
[edit] Null Cell
Is this the same as a Null cell? (Dan 04:20, 25 September 2007 (UTC))
[edit] Rm restructure tag?
Well, I did some restructuring, don't know if what I did is what the tagger had in mind. Should it be removed? If no one responds in a couple days I'll assume no one's interested and remove it myself, since the thing's been tagged since December. Also, I hope someone more familiar with the material will come and simplify the language, since it's a little too technical now. Thanks! delldot talk 03:40, 21 October 2007 (UTC)
[edit] Additions to 'Mechanism'
Added some non-technical info about the general role of NK cells and their MHC-Inhibition. Also drew a little diagram to go along with it. Is it comprehensible?
--Cacofonie (talk) 05:04, 20 December 2007 (UTC)
[edit] Excuse me
I really have no knowledge of this cell or any other cell, in great detail for that matter, but I have a question, that I'm hoping will be able to be answered. Since all cells originate from one main cell, and they are essentially capable to do any job, or function in the body, could these natural killer cells be artificially made? And then used as a...a medicine of sorts for cancer? --AngelicDemon92 (talk) 23:38, 26 March 2008 (UTC)
Yes, Natural Killer cells can be generated from stem cells and clinical protocols for cancer treatment will be developed.--84.160.104.212 (talk) 20:43, 21 May 2008 (UTC)
