Talk:Mothers against decapentaplegic homolog 4

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[edit] Mother's against decapentaplegic homolog 4 Nomenclature

The SMAD family of proteins have a very interesting official name. In the early days of especially, Drosophila research, scientists involved in naming these protein products decided to give these proteins fun names. Unfortunately, this practice is no longer encouraged as most genes today are named systematically and given names that describe the genes/protein's function. A well known example is Sonic hedgehog which is literally named after the video game character Sonic the Hedgehog (character). [edit]

[edit] Note to Patrollers

Before you delete this page check out the links on the page to see if the information on it is accurate, in particular, the name.

[edit] PBB Content

SMAD family member 4
PDB rendering based on 1dd1.
Available structures: 1dd1, 1g88, 1mr1, 1u7f, 1u7v, 1ygs
Identifiers
Symbol(s)	SMAD4; DPC4; JIP; MADH4
External IDs	OMIM: 600993 MGI: 894293 HomoloGene: 31310
Gene ontology Molecular Function: • transcription factor activity • transcription cofactor activity • protein binding • transcription activator activity Cellular Component: • intracellular • nucleus • transcription factor complex • cytoplasm Biological Process: • ureteric bud branching • kidney development • transcription • SMAD protein complex assembly • negative regulation of cell proliferation • anterior/posterior pattern formation • gastrulation (sensu Mammalia) • positive regulation of transcription from RNA polymerase II promoter • regulation of binding
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	4089	17128
Ensembl	ENSG00000141646	ENSMUSG00000024515
Uniprot	Q13485	Q6GTP6
Refseq	NM_005359 (mRNA) NP_005350 (protein)	XM_001001632 (mRNA) XP_001001632 (protein)
Location	Chr 18: 46.81 - 46.86 Mb	Chr 18: 73.76 - 73.83 Mb
Pubmed search	[1]	[2]

If anyone would like to incorporate any ProteinBoxBot content into this page, feel free. But didn't want to replace the existing infobox with something that is not obviously better... AndrewGNF 05:38, 5 November 2007 (UTC)