Millard-Gubler syndrome

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Millard-Gubler syndrome Classification and external resources
ICD-10	G 46.3
ICD-9	344.89
eMedicine	pmr/189

Millard-Gubler syndrome is a lesion of the pons.^[1]

1 Presentation
2 Diagnosis
3 See also
4 References
5 External links

[edit] Presentation

It is a syndrome of unilateral softening of the brain tissue arising from obstruction of the blood vessels of the pons, involving the sixth and seventh cranial nerves and fibers of the corticospinal tract, and is associated with paralysis of the abducens (including diplopia, internal strabismus, and loss of power to rotate the affected eye outward) and facial nerves and contralateral hemiplegia of the extremities.

[edit] Diagnosis

This syndrome is easier to diagnose today thanks to the technical advances in brain imaging (CT, MRI).

[edit] See also

Cerebral softening

[edit] References

^ Anatomy 530a at UWO (Functional Neuroanatomy)

[edit] External links

-1402273782 at GPnotebook
synd/1692 at Who Named It

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v • d • e Pathology of the nervous system, primarily CNS (G00-G47, 320-349)

Inflammatory diseases of the CNS	Meningitis (Arachnoiditis) - Encephalitis - Myelitis - Encephalomyelitis (Acute disseminated) - Tropical spastic paraparesis - Cavernous sinus thrombosis

Systemic atrophies primarily affecting the CNS	Huntington's Spinocerebellar ataxia (Friedreich's ataxia, Ataxia telangiectasia, Hereditary spastic paraplegia) Spinal muscular atrophy: Werdnig-Hoffman - Kugelberg-Welander - Fazio Londe - MND (ALS, PMA, PBP, PP, PLS)

Extrapyramidal and movement disorders	Parkinson's disease - Neuroleptic malignant syndrome - Postencephalitic parkinsonism - Pantothenate kinase-associated neurodegeneration - Progressive supranuclear palsy - Striatonigral degeneration Dystonia/Dyskinesia (Spasmodic torticollis, Meige's, Blepharospasm) Essential tremor - Myoclonus - Lafora Chorea (Choreoathetosis) - Restless legs - Stiff person

Other degenerative/ demyelinating diseases	dementia: Alzheimer's - Pick's - Dementia with Lewy bodies - Frontotemporal lobar degeneration mitochondrial disease: Leigh's demyelinating: Multiple sclerosis - Devic's - Central pontine myelinolysis - Transverse myelitis - Marchiafava-Bignami disease - CAMFAK syndrome - Alpers'

Seizure/epilepsy	Focal (Simple partial, Complex partial) - Generalised (Tonic-clonic, Absence, Atonic, Benign familial neonatal) Lennox-Gastaut - West - Epilepsia partialis continua - Status epilepticus (Complex partial status epilepticus)

Headache	Migraine (Familial hemiplegic) - Cluster - Vascular - Tension

Vascular	Transient ischemic attack (Amaurosis fugax, Transient global amnesia) Cerebrovascular disease (MCA, ACA, PCA, Foville's, Millard-Gubler, Lateral medullary, Weber's, Lacunar stroke)

Sleep disorders	Insomnia - Hypersomnia - Sleep apnea (Ondine's curse) - Narcolepsy - Cataplexy - Kleine-Levin - Circadian rhythm sleep - Delayed sleep phase - Advanced sleep phase

Intracranial hypertension	Hydrocephalus (Normal pressure) - Idiopathic intracranial hypertension

Other encephalopathy	Brain herniation - Cerebral edema - Reye's

Other spinal cord disease	Syringomyelia - Syringobulbia - Morvan's syndrome - Spinal cord compression

v • d • e

Lesions of spinal cord and brain

Spinal cord

sensory: Sensory ataxia - Tabes dorsalis

motor: Motor neurone disease

mixed: Brown-Séquard syndrome - cord syndrome (Posterior, Anterior, Central/Syringomyelia) - Subacute combined degeneration of spinal cord (B12)

Anterior spinal artery syndrome

Brainstem

Medulla (CN 8, 9, 10, 12)	Lateral medullary syndrome/Wallenberg (PICA) - Medial medullary syndrome (ASA)

Pons (CN 5, 6, 7, 8)	Lateral pontine syndrome (AICA) - Millard-Gubler syndrome (lateral) - Medial pontine syndrome (basilar) - Foville's syndrome (dorsal, basilar) - Locked-In syndrome (ventral) - Internuclear ophthalmoplegia - One and a half syndrome

Midbrain (CN 3, 4)	Weber's syndrome (ventral peduncle, PCA) - Benedikt's syndrome (ventral tegmentum, PCA) - Parinaud's syndrome (dorsal, tumor)