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Methocarbamol - Wikipedia, the free encyclopedia

Methocarbamol

From Wikipedia, the free encyclopedia

Methocarbamol
Systematic (IUPAC) name
[2-hydroxy-3-(2-methoxyphenoxy)-propyl] aminoformate
Identifiers
CAS number 532-03-6
ATC code M03BA03
PubChem 4107
DrugBank APRD01102
Chemical data
Formula C11H15NO5 
Mol. mass 241.241 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 1.14-1.24 hours[1]
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral, intravenous

Methocarbamol (trade names Robaxin, Robaxacet, and Robax Platinum) is a central muscle relaxant used to treat skeletal muscle spasms. It is structurally related to guaifenesin, and produces guaifenesin in the body as a metabolite.

A combination of methocarbamol and aspirin is marketed as Robaxisal.

[edit] References

  1. ^ Sica DA, Comstock TJ, Davis J, Manning L, Powell R, Melikian A, Wright G. (1990). "Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals". European Journal of Clinical Pharmacology 39 (2): 193–4. doi:10.1007/BF00280060. PMID 2253675. 


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