LUC7L

From Wikipedia, the free encyclopedia

LUC7-like (S. cerevisiae)

Identifiers

LUC7L; FLJ10231; LUC7-LIKE; LUC7B1; SR+89

External IDs

OMIM: 607782 MGI: 1914228 HomoloGene: 69446

Gene ontology
Molecular Function:	• zinc ion binding • metal ion binding
Cellular Component:	• nucleus
Biological Process:	• negative regulation of striated muscle development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018032 (mRNA)
NP_060502 (protein)

NM_025881 (mRNA)
NP_080157 (protein)

Location

Chr 16: 0.18 - 0.22 Mb

Chr 17: 25.98 - 26.01 Mb

Pubmed search

[1]

[2]

LUC7-like (S. cerevisiae), also known as LUC7L, is a human gene.^[1]

The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al., 2001).[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: LUC7L LUC7-like (S. cerevisiae).

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.". Hum. Mol. Genet. 10 (4): 339–52. PMID 11157797.
Tufarelli C, Frischauf AM, Hardison R, et al. (2001). "Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain.". Genomics 71 (3): 307–14. doi:10.1006/geno.2000.6394. PMID 11170747.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.". Mol. Cell 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.