LCMT1

From Wikipedia, the free encyclopedia

Leucine carboxyl methyltransferase 1

Identifiers

LCMT1; CGI-68; LCMT; PPMT1

External IDs

OMIM: 610286 MGI: 1353593 HomoloGene: 41123

Gene ontology
Molecular Function:	• C-terminal protein carboxyl methyltransferase activity • protein binding • S-adenosylmethionine-dependent methyltransferase activity • transferase activity
Biological Process:	• protein modification process • C-terminal protein amino acid methylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_001032391 (mRNA)
NP_001027563 (protein)

NM_025304 (mRNA)
NP_079580 (protein)

Location

Chr 16: 25.03 - 25.1 Mb

Chr 7: 123.17 - 123.22 Mb

Pubmed search

[1]

[2]

Leucine carboxyl methyltransferase 1, also known as LCMT1, is a human gene.^[1]

[edit] References

^ Entrez Gene: LCMT1 leucine carboxyl methyltransferase 1.

[edit] Further reading

Lee JA, Pallas DC (2007). "Leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cells.". J. Biol. Chem. 282 (42): 30974-84. doi:10.1074/jbc.M704861200. PMID 17724024.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703-13. PMID 10810093.
De Baere I, Derua R, Janssens V, et al. (2000). "Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue.". Biochemistry 38 (50): 16539-47. PMID 10600115.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.