From Wikipedia, the free encyclopedia
HLA-B54 (B54) is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56.[1] The serotype identifies the more common HLA-B*55 gene products.[2] (For terminology help see: HLA-serotype tutorial)
[edit] Serotype
B54 and B22 serotype recognition of HLA B*5401 allele[3]
| B*54 |
B54 |
B22 |
Sample |
| allele |
% |
% |
size (N) |
| 5401 |
67 |
3 |
631 |
[edit] Allele distribution
HLA B*5401 frequencies
|
|
freq |
| ref. |
Population |
(%) |
| [4] |
USA Hawaii Okinawa |
10.6 |
| [4] |
Japan Central |
7.7 |
| [4] |
South Korea (3) |
5.9 |
| [4] |
China Guangzhou |
4.5 |
| [4] |
Thailand (3) |
4.1 |
| [4] |
China Inner Mongolia |
3.4 |
| [4] |
China North Han |
3.3 |
| [4] |
China Beijing Shijiazhuang Tianjian Han |
3.0 |
| [4] |
China South Han |
2.5 |
| [4] |
Russia Tuva pop 2 |
2.2 |
| [4] |
China Guangxi Maonan |
1.9 |
| [4] |
Thailand |
1.8 |
| [4] |
Taiwan Thao |
1.7 |
| [4] |
China Tibet Autonomous Region Tibetans |
1.3 |
[edit] References
- ^ Hildebrand WH, Madrigal JA, Little AM, Parham P (1992). "HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix". J. Immunol. 148 (4): 1155–62. PMID 1737933.
- ^ Marsh SG, Albert ED, Bodmer WF, et al (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
- ^ derived from IMGT/HLA
- ^ a b c d e f g h i j k l m n Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. PMID 12753660.
