Glycerol dehydrogenase (NADP+)

From Wikipedia, the free encyclopedia

In enzymology, a glycerol dehydrogenase (NADP+) (EC 1.1.1.72) is an enzyme that catalyzes the chemical reaction

glycerol + NADP⁺ D-glyceraldehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are glycerol and NADP⁺, whereas its 3 products are D-glyceraldehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycerol:NADP+ oxidoreductase. This enzyme is also called glycerol dehydrogenase (NADP+). This enzyme participates in glycerolipid metabolism.

[edit] References

• IUBMB entry for 1.1.1.72
• BRENDA references for 1.1.1.72 (Recommended.)
• PubMed references for 1.1.1.72
• PubMed Central references for 1.1.1.72
• Google Scholar references for 1.1.1.72
• Kormann AW, Hurst RO, Flynn TG (1972). "Purification and properties of an NADP + -dependent glycerol dehydrogenase from rabbit skeletal muscle". Biochim. Biophys. Acta. 258: 40–55. PMID 4400494. 
• Toews CJ (1967). "The kinetics and reaction mechanism of the nicotinamide-adinine dinucleotide phosphate-specific glycerol dehydrogenase of rat skeletal muscle". Biochem. J. 105: 1067–1073. 

[edit] External links

The CAS registry number for this enzyme class is 37250-11-6.

• IUBMB entry for 1.1.1.72

• KEGG entry for 1.1.1.72

• BRENDA entry for 1.1.1.72

• NiceZyme view of 1.1.1.72

• EC2PDB: PDB structures for 1.1.1.72

• PRIAM entry for 1.1.1.72

• PUMA2 entry for 1.1.1.72

• IntEnz: Integrated Enzyme entry for 1.1.1.72

• MetaCyc entry for 1.1.1.72

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047956: glycerol dehydrogenase (NADP+)

• AMIGO entry for GO code 0047956: glycerol dehydrogenase (NADP+)