fis
From Wikipedia, the free encyclopedia
 |
This article does not cite any references or sources. (December 2007) Please help improve this article by adding citations to reliable sources. Unverifiable material may be challenged and removed. |
For other uses, see Factor for Inversion Stimulation (disambiguation).
fis is the E. coli gene encoding FIS protein. The regulation of this gene is more complex than most other genes in the E. coli genome, as FIS is an important protein which regulates expression of other genes. It is supposed that fis is regulated by H-NS, IHF_(protein) and CRP. It also regulates its own expression (autoregulation).
FIS buffers decrease of negative supercoiling in tyrT and rrnA expression. The upstream FIS binding site of rrnA is required for this and it's probable that FIS enables local DNA curvature. See Travers and Muskhelishvili 2005 for more detail.
 |
This genetics article is a stub. You can help Wikipedia by expanding it. |
 |
This bacteria-related article is a stub. You can help Wikipedia by expanding it. |
