Entactin
From Wikipedia, the free encyclopedia
Nidogen 1
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PDB rendering based on 1gl4. | ||||||||||||||
Available structures: 1gl4, 1h4u | ||||||||||||||
Identifiers | ||||||||||||||
Symbol(s) | NID1; NID | |||||||||||||
External IDs | OMIM: 131390 MGI: 97342 HomoloGene: 1878 | |||||||||||||
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RNA expression pattern | ||||||||||||||
Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 4811 | 18073 | ||||||||||||
Ensembl | ENSG00000116962 | n/a | ||||||||||||
Uniprot | P14543 | n/a | ||||||||||||
Refseq | NM_002508 (mRNA) NP_002499 (protein) |
NM_010917 (mRNA) NP_035047 (protein) |
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Location | Chr 1: 234.21 - 234.3 Mb | n/a | ||||||||||||
Pubmed search | [1] | [2] |
Entactin (or nidogen) is a component of the basement membrane alongside other components such as collagen type IV, proteoglycans ( heparan sulfate and glycosaminoglycans), laminin and fibronectin.
This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix.[1]
[edit] References
[edit] Further reading
- Chung AE, Durkin ME (1990). "Entactin: structure and function.". Am. J. Respir. Cell Mol. Biol. 3 (4): 275–82. PMID 2119632.
- Yurchenco PD, Schittny JC (1990). "Molecular architecture of basement membranes.". FASEB J. 4 (6): 1577–90. PMID 2180767.