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DnaX ribosomal frameshifting element - Wikipedia, the free encyclopedia

DnaX ribosomal frameshifting element

From Wikipedia, the free encyclopedia

DnaX ribosomal frameshifting element
Template:Abbreviation
Type: Cis-reg; frameshift_element;
2° structure: Published; PubMed
Seed alignment: PubMed
Avg length: 65.0 nucleotides
Avg identity: 85%

The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two encoded products tau and gamma which are produced in a 1:1 ratio. The gamma protein is synthesised due to programmed frameshifting and is shorter than tau. The two products of the dnaX gene are DNA polymerase III subunits.[1] [2]

[edit] References

  1. ^ Larsen, B; Gesteland RF, Atkins JF (1997). "Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: programmed efficiency of 50%". J Mol Biol 271: 47–60. doi:10.1006/jmbi.1997.1162. PMID 9300054. 
  2. ^ Blinkova, A; Burkart MF, Owens TD, Walker JR (1997). "Conservation of the Escherichia coli dnaX programmed ribosomal frameshift signal in Salmonella typhimurium". J Bacteriol 179: 4438–4442. PMID 9209069. 

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