Talk:Calcium channel blocker
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- "Many calcium channel blockers also slow down the conduction of electrical activity within the heart, by blocking the calcium channel during the plateau phase of the action potential of the heart (see: cardiac action potential). This is known as a negative dromotropic effect."
Maybe this sentence should be changed. My understanding of dromotropism is that it specifically refers to trasnmission through the AV node. User:boruchfishman May 20, 2008 —Preceding unsigned comment added by 169.132.18.249 (talk) 12:58, 20 May 2008 (UTC)
- "With low blood pressure, the heart does not have to work as hard, this can ease problems with cardiac myopathy and coronary disease."
Maybe the above sentence should be removed, given that calcium channel blockers have a relative contraindication in the setting of ischemic heart disease? Ksheka 16:29, Jun 19, 2004 (UTC)
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[edit] Why no mention of male contraceptive effect?
The article on male contraceptives says that calcium channel blocker drugs act as a male contraceptive by "interfering with the sperms’ ability to swim properly or preventing sperm from recognizing or binding to an egg". Why is this not mentioned in this article? --Cohen the Bavarian 19:40, 18 June 2006 (UTC)
Because it is not true, nothing has been published showing any contraceptive effect of calcium channel blockers.
[edit] How about azelnidipine, the new CCB that is approved in Japan?
[edit] Magnesium
The part about the pharmaceutical industry taking over this website is not necessary and adds nothing to the page. There is no reference given to support the use of Magnesium in lowering heart rate. It is not relevant to this page. 86.132.104.167 17:07, 2 April 2007 (UTC)
- Indeed. I've commented out the section, hopefully it will be rewritten with proper sources in due time. Fvasconcellos 19:47, 2 April 2007 (UTC)
[edit] The material in this article appears to be copyright infringing
Although neither the Wikipedia page nor the other webpage I noted which seem to have nearly identical text list any sources, it is hard to say who is stealing from whom. Of course, if Dr. Klabunde is lifting from Wikipedia that is legal, but if whoever wrote the Wikipedia entry cut and pasted from Dr. Klabunde's page, we have a problem. It is beyond me to understand how this is decided or handled.
