Apt-Downey test
From Wikipedia, the free encyclopedia
 |
This article is orphaned as few or no other articles link to it. Please help introduce links in articles on related topics. (May 2008) |
 |
This article or section includes a list of references or external links, but its sources remain unclear because it lacks in-text citations. You can improve this article by introducing more precise citations. |
 |
This article may require cleanup to meet Wikipedia's quality standards. Please improve this article if you can. (May 2008) |
The Apt-Downey test is used to help differentiate between maternal from baby blood.
The blood is placed in a test tube; sterile water is added to hemolyze the RBCs, yielding free hemoglobin.
This solution then is mixed with 1% sodium hydroxide. If the solution turns yellow-brown, the hemoglobin is maternal or adult hemoglobin, which is less stable than fetal hemoglobin.
If the solution remains the same color, it is the more stable fetal hemoglobin; therefore, the newborn is the source of the bleeding.[1]
[edit] References
Pediatric Gastrointestinal Bleeding, emedicine, Renee Y Hsia, MD, MSc, Faculty, Department of Emergency Medicine, University of California at San Francisco; Attending Physician, Emergency Medicine, San Francisco General Hospital
"My two-week old daughter is throwing up blood", Moustafa MH, Taylor, MD, Fletcher L. Los Angeles County-Martin Luther King Jr./Drew Medical Center, 12021 South Wilmington Avenue, Los Angeles, CA 90059, USA.
- http://www.emedicine.com/emerg/topic381.htm
- http://www.blackwellpublishing.com/journal.asp?ref=1069-6563&site=1
