Benutzer:Cord Uebermuth
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Cord Uebermuth Facharzt für Augenheilkunde
Kontakt: 0176/96376517 email: Augenheilkunde@gmx.de homepage: www.klasse-augen.de Wohnort: Düsseldorf
Interessenschwerpunkte: Augenheilkunde (gesamtes Spektrum, einschliesslich Uveitis, Glaukom, AMD, Netzhaut, diabetische Netzhautschädigungen), Borreliose und andere Zeckenübertragene Erkrankungen - Immunologie und Pathophysiologie, Aktienresearch mit Schwerpunkt Technische Analyse und Biotechwerte, Musik, Philosophie.
Individuelle Borrelioseberatung nur nach Rücksprache - keine Borreliosebehandlung - zur Zeit nicht in eigener Praxis tätig.
[Bearbeiten] Wissenschaftliche Abhandlungen:
1. Die Muzine des äusseren Auges
- erschienen im Ophthalmologen 1999:
Title: [Mucins of the eye]
Author: Uebermuth C Source: Ophthalmologe, 96(9): 563-9 1999
Abstract: BACKGROUND: The present knowledge about ocular mucins is presented. RESULTS: Mucins are glycoproteins of high polymer structure. Following the classification of the Human Gene Mapping Committee, they are subdivided in MUC1-9. They are an important component of the tear film and are found in conjunctival and corneal ocular surface epithelia. The mucins of the ocular surface epithelia belong to MUC1, MUC4 and MUC5AC. The existence of MUC2 is in doubt and controversial in the scientific literature. However, a mucin-associated peptide that belongs to the group of trefoil peptides was found in the goblet cells. It is the intestinal trefoil factor (ITF) that seems to interact with mucins during reepithelization in other organs and in cell culture. Unclear is the significance of oligosaccharid structures of mucins like Tn and sialosyl-Tn, which are found in the surface epithelia of the eye. CONCLUSION: Further investigation will be necessary to answer many open questions concerning the existence, significance and function of ocular mucins. Language: ger Unique Identifier: MajorMeSH Heading: Muscle Proteins, Neuropeptides MinorMeSH Heading Conjunctiva, English Abstract, Epithelium, Epithelium, Corneal, Growth Substances, Humans, Mucins, Peptides
2. Zunächst einseitige, später beidseitige Optikopathie - ist Amiodaron die Ursache?
Title: [First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?] Author: Uebermuth CA , Gerke E Source: Ophthalmologe, 99(6): 470-3 2002
Abstract: CASE REPORT: Amiodarone has many severe side-effects and can cause keratopathy and neuropathy. We report the case of a 79-year-old male patient with progressive visual loss and papilloedema of the right eye during therapy with amiodarone. To reduce papilloedema he was treated with corticosteroids. Amiodarone therapy was then discontinued, but there was no considerable improvement and after 6 weeks visual loss occurred in the left eye as well. CONCLUSION: With regard to the findings we consider this case to be an amiodarone-induced optic neuropathy. According to our knowledge only 19 cases have been reported in the literature but the results of one study indicate that the incidence of optic neuropathy is as high as 1.79%. The pathophysiology of the optic nerve damage remains unclear and an effective treatment is not available. It might be possible that the accelerated elimination of amiodarone with colestyramine could be suitable to prevent optic neuropathy of the second eye. Language: ger Unique Identifier: MinorMeSH Heading Aged, Amiodarone, Anti-Arrhythmia Agents, Arrhythmia, Blindness, Dose-Response Relationship, Drug, English Abstract, Humans, Male, Optic Nerve Diseases, Papilledema, Visual Fields
3. Poster auf der Versammlung der Deutschen Opthalmologischen Gesellschaft - DOG 2003 - Berlin
Titel: Tropheryma whippelii - harmloser Komensale oder tödlicher Keim?
Ein Fallbericht.
Seit 2004 wissenschaftliches Schwerpunktinteresse auf aktuellen Themen der Augenheilkunde (AMD-Therapie u.a.) und Zeckenübertragene Erkrankungen (einschliesslich Diagnose und Therapie der Borreliose und andere Zeckenassozierter Erkrankungen)
