LGALS3

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Lectin, galactoside-binding, soluble, 3
PDB rendering based on 1a3k.
Available structures: 1a3k, 1kjl, 1kjr, 2nmn, 2nmo, 2nn8
Identifiers
Symbol(s)	LGALS3; LGALS2; CBP35; GAL3; GALBP; GALIG; MAC2
External IDs	OMIM: 153619 MGI: 96778 HomoloGene: 37608
Gene ontology Molecular Function: • protein binding • sugar binding • IgE binding Cellular Component: • extracellular region • proteinaceous extracellular matrix • nucleus • cytoplasm • plasma membrane Biological Process: • skeletal development • extracellular matrix organization and biogenesis
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	3958	16854
Ensembl	ENSG00000131981	ENSMUSG00000050335
Uniprot	P17931	Q3V471
Refseq	NM_194327 (mRNA) NP_919308 (protein)	NM_010705 (mRNA) NP_034835 (protein)
Location	Chr 14: 54.67 - 54.68 Mb	Chr 14: 46.3 - 46.31 Mb
Pubmed search	[1]	[2]

Lectin, galactoside-binding, soluble, 3, also known as LGALS3, is a human gene.^[1]

[edit] See also

• Galectin

[edit] References

1. ^ Entrez Gene: LGALS3 lectin, galactoside-binding, soluble, 3.

[edit] Further reading

• Barondes SH, Cooper DN, Gitt MA, Leffler H (1994). "Galectins. Structure and function of a large family of animal lectins.". J. Biol. Chem. 269 (33): 20807–10. PMID 8063692. 
• Nakahara S, Oka N, Raz A (2005). "On the role of galectin-3 in cancer apoptosis.". Apoptosis 10 (2): 267–75. doi:10.1007/s10495-005-0801-y. PMID 15843888. 
• Fukumori T, Kanayama HO, Raz A (2007). "The role of galectin-3 in cancer drug resistance.". Drug Resist. Updat. 10 (3): 101–8. doi:10.1016/j.drup.2007.04.001. PMID 17544840. 

This article on a gene on chromosome 14 is a stub. You can help Wikipedia by expanding it.

Categories: Genes on chromosome 14 | Human proteins | Chromosome 14 gene stubs

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• This page was last modified 21:15, 9 June 2008 by Wikipedia user DOI bot. Based on work by Wikipedia user(s) Alaibot and Banus.
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