Draculin
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Draculin is a glycoprotein found in the saliva of vampire bats. It is composed of 411 amino acids. It functions as an anticoagulant, inhibiting coagulation factors IX (IXa) and X (Xa), thus keeping the blood of the bitten victim from clotting while the bat is drinking. This anticoagulant is twenty times stronger than any other known anticoagulant and is prescribed for heart attack and stroke patients.
[edit] External links
- Fernandez AZ, Tablante A, Bartoli F, Beguin S, Hemker HC, Apitz-Castro R. Expression of biological activity of draculin, the anticoagulant factor from vampire bat saliva, is strictly dependent on the appropriate glycosylation of the native molecule. Biochim Biophys Acta 1998;1425:291-9. PMID 9795244.
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