CEACAM7

From Wikipedia, the free encyclopedia

Carcinoembryonic antigen-related cell adhesion molecule 7

Identifiers

CEACAM7; CEA; CGM2

External IDs

Gene ontology
Molecular Function:	• GPI anchor binding
Cellular Component:	• plasma membrane • integral to membrane

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

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Refseq

NM_006890 (mRNA)
NP_008821 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 19: 46.87 - 46.88 Mb

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Pubmed search

[1]

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Carcinoembryonic antigen-related cell adhesion molecule 7, also known as CEACAM7, is a human gene.^[1]

[edit] References

^ Entrez Gene: CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7.

[edit] Further reading

Douard R, Wind P, Sales JP, et al. (2006). "Long-term prognostic value of detection of circulating colorectal cancer cells using CGM2 reverse transcriptase-polymerase chain reaction assay.". Surgery 139 (4): 556–62. doi:10.1016/j.surg.2005.09.025. PMID 16627067.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161.
Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Schölzel S, Zimmermann W, Schwarzkopf G, et al. (2000). "Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas.". Am. J. Pathol. 156 (2): 595–605. PMID 10666389.
Frängsmyr L, Baranov V, Hammarström S (1999). "Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.". Tumour Biol. 20 (5): 277–92. PMID 10436421.
Kinugasa T, Kuroki M, Takeo H, et al. (1998). "Expression of four CEA family antigens (CEA, NCA, BGP and CGM2) in normal and cancerous gastric epithelial cells: up-regulation of BGP and CGM2 in carcinomas.". Int. J. Cancer 76 (1): 148–53. PMID 9533775.
Thompson J, Seitz M, Chastre E, et al. (1997). "Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis.". Cancer Res. 57 (9): 1776–84. PMID 9135022.
Thompson J, Zimmermann W, Nollau P, et al. (1995). "CGM2, a member of the carcinoembryonic antigen gene family is down-regulated in colorectal carcinomas.". J. Biol. Chem. 269 (52): 32924–31. PMID 7806520.
Thompson JA, Mauch EM, Chen FS, et al. (1989). "Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons.". Biochem. Biophys. Res. Commun. 158 (3): 996–1004. PMID 2537643.
Khan WN, Frängsmyr L, Teglund S, et al. (1992). "Identification of three new genes and estimation of the size of the carcinoembryonic antigen family.". Genomics 14 (2): 384–90. PMID 1427854.