Calponin
From Wikipedia, the free encyclopedia
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calponin 1, basic, smooth muscle
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| Identifiers | |
| Symbol | CNN1 |
| Entrez | 1264 |
| HUGO | 2155 |
| OMIM | 600806 |
| RefSeq | NM_001299 |
| UniProt | P51911 |
| Other data | |
| Locus | Chr. 19 p13.2-13.1 |
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calponin 2
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| Identifiers | |
| Symbol | CNN2 |
| Entrez | 1265 |
| HUGO | 2156 |
| OMIM | 602373 |
| RefSeq | NM_004368 |
| UniProt | Q99439 |
| Other data | |
| Locus | Chr. 21 q11.1 |
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calponin 3, acidic
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| Identifiers | |
| Symbol | CNN3 |
| Entrez | 1266 |
| HUGO | 2157 |
| OMIM | 602374 |
| RefSeq | NM_001839 |
| UniProt | Q6FHA7 |
| Other data | |
| Locus | Chr. 1 p22-p21 |
Calponin is a calcium binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein kinase (which is dependent upon Calcium binding to calmodulin) releases the calponin's inhibition of the smooth muscle ATPase.
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