5-dehydro-2-deoxyphosphogluconate aldolase

From Wikipedia, the free encyclopedia

In enzymology, a 5-dehydro-2-deoxyphosphogluconate aldolase (EC 4.1.2.29) is an enzyme that catalyzes the chemical reaction

5-dehydro-2-deoxy-D-gluconate 6-phosphate glycerone phosphate + malonate semialdehyde

Hence, this enzyme has one substrate, 5-dehydro-2-deoxy-D-gluconate 6-phosphate, and two products, glycerone phosphate and malonate semialdehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (glycerone-phosphate-forming). Other names in common use include phospho-5-keto-2-deoxygluconate aldolase, 5-dehydro-2-deoxy-D-gluconate-6-phosphate, and malonate-semialdehyde-lyase.

[edit] References

• IUBMB entry for 4.1.2.29
• BRENDA references for 4.1.2.29 (Recommended.)
• PubMed references for 4.1.2.29
• PubMed Central references for 4.1.2.29
• Google Scholar references for 4.1.2.29
• Anderson WA, Magasanik B (1971). "The pathway of myo-inositol degradation in Aerobacter aerogenes Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates". J. Biol. Chem. 246: 5662–75. PMID 4328832. 

[edit] External links

The CAS registry number for this enzyme class is 62213-25-6.

• IUBMB entry for 4.1.2.29

• KEGG entry for 4.1.2.29

• BRENDA entry for 4.1.2.29

• NiceZyme view of 4.1.2.29

• EC2PDB: PDB structures for 4.1.2.29

• PRIAM entry for 4.1.2.29

• PUMA2 entry for 4.1.2.29

• IntEnz: Integrated Enzyme entry for 4.1.2.29

• MetaCyc entry for 4.1.2.29

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047441: 5-dehydro-2-deoxyphosphogluconate aldolase

• AMIGO entry for GO code 0047441: 5-dehydro-2-deoxyphosphogluconate aldolase