SLC27A1

From Wikipedia, the free encyclopedia

Solute carrier family 27 (fatty acid transporter), member 1

Identifiers

SLC27A1; ACSVL5; FATP; FATP1; FLJ00336; MGC71751

External IDs

OMIM: 600691 MGI: 1347098 HomoloGene: 8063

Gene ontology
Molecular Function:	• nucleotide binding • catalytic activity • ligase activity
Cellular Component:	• membrane • integral to membrane
Biological Process:	• lipid metabolic process • fatty acid metabolic process • lipid transport • metabolic process

Orthologs

Human

Mouse

Refseq

NM_198580 (mRNA)
NP_940982 (protein)

NM_011977 (mRNA)
NP_036107 (protein)

Location

Chr 19: 17.44 - 17.48 Mb

Chr 8: 74.5 - 74.52 Mb

Pubmed search

[1]

[2]

Solute carrier family 27 (fatty acid transporter), member 1, also known as SLC27A1, is a human gene.^[1]

[edit] See also

MeSH SLC27A1+protein,+human

[edit] References

^ Entrez Gene: SLC27A1 solute carrier family 27 (fatty acid transporter), member 1.

[edit] Further reading

Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J (2006). "Lack of association between certain candidate gene polymorphisms and the metabolic syndrome.". Mol. Genet. Metab. 86 (1-2): 293-9. doi:10.1016/j.ymgme.2005.05.006. PMID 15978856.
García-Martínez C, Marotta M, Moore-Carrasco R, et al. (2005). "Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells.". Am. J. Physiol., Cell Physiol. 288 (6): C1264-72. doi:10.1152/ajpcell.00271.2004. PMID 15897321.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Gertow K, Skoglund-Andersson C, Eriksson P, et al. (2003). "A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution.". Atherosclerosis 167 (2): 265-73. PMID 12818409.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Hatch GM, Smith AJ, Xu FY, et al. (2003). "FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells.". J. Lipid Res. 43 (9): 1380-9. PMID 12235169.
Martin G, Nemoto M, Gelman L, et al. (2000). "The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression.". Genomics 66 (3): 296-304. doi:10.1006/geno.2000.6191. PMID 10873384.
Hirsch D, Stahl A, Lodish HF (1998). "A family of fatty acid transporters conserved from mycobacterium to man.". Proc. Natl. Acad. Sci. U.S.A. 95 (15): 8625-9. PMID 9671728.
Schaffer JE, Lodish HF (1994). "Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein.". Cell 79 (3): 427-36. PMID 7954810.

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v • d • e Membrane proteins, carrier proteins: membrane transport proteins

ABC-transporter	A1, A2, A3, A4, A7, A8, A12, B1 B2-3, B2, B3, B4, B5, B6, B7, B9, B11 C1, C2, C3, C4, C5, C6, C8, C8-9, C10, C13, C11 D1, D2, D3, D4, E1, F1, F2 G1, G2, G4, Sterolin (G5, G8)

Solute carrier	1A1-7, 1A1, 1A2, 1A3, 1A4, 1A5, 2A1, 2A2, 2A3, 2A4, 2A5, 2A6, 2A8, 2A9, 2A10, 2A12, 3A1, 3A2, 4A1, 4A2, 4A3, 4A4, 4A5, 4A7, 4A8, 4A11, 5A1-2, 5A1, 5A3, 5A5, 5A8, 6A1, 6A2, 6A3, 6A4, 6A5, 6A8, 6A9, 6A19, 7A1, 7A2, 7A3, 7A4, 7A5, 7A7, 7A8, 7A9, 7A11, 8A1-3, 9A1, 9A2, 9A3, 9A3R1, 9A3R2, 9A5, 9A6, 9A8, 10A1, 10A2, 10A3, 10A7, 11A1, 11A2, 11A3, 12A1-2, 12A3, 12A4, 12A5, 12A6, 12A7, 14A1, 13A3, 14A2, 15A1, 15A2, 16A1, 16A2, 16A3, 16A4, 17A1, 17A5, 17A6-8, 17A7, 18A1, 18A2, 18A3, 19A1, 19A2, 19A3, 20A1, 20A2, 22A1, 22A2, 22A3, 22A4, 22A5, 22A6, 22A7, 22A9, 22A11, 22A12, 22A18, 23A1, 23A2, 24A1-2, 24A5, 25A1, 25A3, 25A4, 25A4-6, 25A8, 25A10, 25A11, 25A12, 25A13, 25A14, 25A15, 25A17, 25A19, 25A20, 25A27, 25A31, 25A37, 25A39, 26A2, 26A3, 26A4, 26A5, 26A6, 26A7, 26A8, 27A1, 27A2, 27A3, 27A4, 28A1, 28A2, 29A1, 29A2, 29A4, 30A4, 30A7, 30A8, 31A1, 31A2, 32A1, 34A1, 34A2, 34A3, 35A1, 35A2, 35B2, 35B4, 35C1, 36A1, 37A4, 38A2, 38A3, 39A1, 39A2, 39A3, 39A4, 39A6, 39A7, 40A1, 43A1 44A1, 44A2, 44A4, 45A2, O1A2, O1B1, O1B3, O2B1, O431, O4A1

Monosaccharide	GLUT1, GLUT2, GLUT3, GLUT4, GLUT5, GLUT6, GLUT8, GLUT9

Other	Amino acid (CD98) - Fatty acid (CD36) - Ion channels - Ion pumps - Mitochondrial membrane transport protein - Neurotransmitter transport proteins - Nuclear (Importin, Karyopherin)