LINGO1
From Wikipedia, the free encyclopedia
|
Leucine rich repeat and Ig domain containing 1
|
|||||||||||
 |
|||||||||||
| PDB rendering based on 2id5. | |||||||||||
| Available structures: 2id5 | |||||||||||
| Identifiers | |||||||||||
| Symbol(s) | LINGO1; FLJ14594; LERN1; LRRN6A; MGC17422; UNQ201 | ||||||||||
| External IDs | OMIM: 609791 MGI: 1915522 HomoloGene: 41891 | ||||||||||
|
|||||||||||
| Orthologs | |||||||||||
| Human | Mouse | ||||||||||
| Entrez | 84894 | 235402 | |||||||||
| Ensembl | ENSG00000169783 | ENSMUSG00000049556 | |||||||||
| Refseq | NM_032808 (mRNA) NP_116197 (protein) |
XM_974866 (mRNA) XP_979960 (protein) |
|||||||||
| Location | Chr 15: 75.69 - 75.7 Mb | Chr 9: 56.42 - 56.48 Mb | |||||||||
| Pubmed search | [1] | [2] | |||||||||
Leucine rich repeat and Ig domain containing 1, also known as LINGO1, is a human gene.[1]
[edit] References
[edit] Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:. PMID 12975309.
- Carim-Todd L, Escarceller M, Estivill X, Sumoy L (2004). "LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex.". Eur. J. Neurosci. 18 (12): 3167-82. PMID 14686891.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:. PMID 14702039.
- Mi S, Lee X, Shao Z, et al. (2004). "LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.". Nat. Neurosci. 7 (3): 221-8. doi:. PMID 14966521.
- Shao Z, Browning JL, Lee X, et al. (2005). "TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.". Neuron 45 (3): 353-9. doi:. PMID 15694322.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:. PMID 16189514.
- Mosyak L, Wood A, Dwyer B, et al. (2007). "The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.". J. Biol. Chem. 281 (47): 36378-90. doi:. PMID 17005555.
- Satoh J, Tabunoki H, Yamamura T, et al. (2007). "TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.". Neuropathol. Appl. Neurobiol. 33 (1): 99-107. doi:. PMID 17239012.
- Inoue H, Lin L, Lee X, et al. (2007). "Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models.". Proc. Natl. Acad. Sci. U.S.A. 104 (36): 14430-5. doi:. PMID 17726113.
 |
This article on a gene on chromosome 15 is a stub. You can help Wikipedia by expanding it. |
